슬관절 연골 결손에 대한 fibrin matrix 자가 연골 세포 이식술 후 임상적 결과와 자기공명 영상 소견 및 운동력 회복

초록

The purpose of this study was to evaluate the clinical results, MRI findings and recovery of sports activity in 11 patients with cartilage defects of the knee who received fibrin matrix autologous chondrocyte implantation (ACI) from December 2005 to February 2008. Their mean age at the time of surgery was 37.8 years and the mean follow-up was 24.1 months. The average size of defect was 6.27 cm². The site of defect was located in medial femoral condyle or lateral tibial condyle. Clinical results were assessed using the Lysholm score, VAS score, modified Cincinnati knee score, Tegner activity scores. MRI was examined at 12 months postimplantation. The quadriceps and hamstrings strength were measured using Biodex System. Mean modified Cincinnati score, VAS score, Lysholm score and Tegner activity scores were showed significant improvement. MRI studies also were showed significant improvement. Peak torque and total work at postoperative period were significantly greater than at preoperative period. The treatment of chondral lesions of the knee using ACI brought positive clinical results. It has been shown that ACI is an effective means of managing focal chondral lesions of the knee. The clinical, MRI findings and recovery of sports activity reflect the good outcome obtained with the procedure.

키워드