Nanoparticle-based energy transfer for rapid and simple detection of protein glycosylation

Oh, Eunkeu; Lee, Dohoon; Kim, Young-Pil; Cha, Seung Youp; Oh, Doo-Beyong; Kang, Hyun Ah; Kim, Jungbae; Kim, Hak-Sung

doi:10.1002/anie.200601948

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Nanoparticle-based energy transfer for rapid and simple detection of protein glycosylation

Oh, Eunkeu;
Lee, Dohoon;
Kim, Young-Pil;
Cha, Seung Youp;
Oh, Doo-Beyong;
... Kang, Hyun Ah;
외 2명

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77

초록

(Figure Presented) Photoluminescence quenching of dextranconjugated quantum dots (dex-QDs) by gold nanoparticles conjugated with concanavalin A (conA-AuNPs) can be prevented by adding a glycoprotein, which inhibits the association of dex-QDs with conA-AuNPs (see scheme). This phenomenon can be used as an analytical tool for the detection of protein glycosylation. PL = photoluminescence. © 2006 Wiley-VCH Verlag GmbH & Co. KGaA.

키워드

Carbohydrates; Energy transfer; Glycoproteins; Gold nanoparticles; Quantum dots; QUANTUM DOTS; HANSENULA-POLYMORPHA; GOLD NANOPARTICLES; GLUCOSE-OXIDASE; FLUORESCENCE; OLIGOSACCHARIDES; GLYCOPROTEINS; PARTICLES; AFFINITY

제목: Nanoparticle-based energy transfer for rapid and simple detection of protein glycosylation

저자: Oh, Eunkeu; Lee, Dohoon; Kim, Young-Pil; Cha, Seung Youp; Oh, Doo-Beyong; Kang, Hyun Ah; Kim, Jungbae; Kim, Hak-Sung

DOI: 10.1002/anie.200601948

발행일: 2006-12

유형: Article

저널명: Angewandte Chemie International Edition

권: 45

호: 47

페이지: 7959 ~ 7963

언어: ENG

출판사: WILEY-V C H VERLAG GMBH

발행국가: 독일

분량: 5 페이지

ISSN: E 1521-3773
P 1433-7851