알코올 사용 장애에서 양극성 장애 선별 질문지들의 타당성 및 임상적 유용성 비교를 위한 예비연구

초록

Objectives : The objective of this study is to evaluate the validity of the Korean version of Mood Disorder Questionnaire (K-MDQ), the Korean version of Hypomania Checklist-32 (K-HCL-32) and the Korean version of Bipolar spectrum diagnostic scale (K-BSDS) as screening tools for bipolar disorder (BD) in patients with alcohol use disorder. Methods : 161 admitted patients with alcohol use disorder completed the K-MDQ, K-HCL-32, K-BSDS and all participants were assessed with the Structured Clinical Interview for DSM-IV to diagnose BD. Results : Among 161 patients with alcohol use disorder, 21 patients (13.0%) met criteria for a lifetime diagnosis of bipolar I disorder. In this study, we found that scores associated with increased energy and sexual activity are significantly high in comorbid group while scores associated with irritability/impulsivity are not. The K-HCL-32 showed higher sensitivity (0.809) and specificity (0.742) than K-MDQ or K-BSDS with cut-off score of 16. Conclusion : These results indicate that among the three screening tools for bipolar disorder, K-HCL-32 is the most valid and useful tool in alcohol use disorder patients with cut-off score of 16. In addition, this study propose that questions about increased energy and sexual activity are key point for detecting BD in alcohol use disorder patients.

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