Electrochemical hydrotrifluoromethylation of alkynes
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초록

We report the electrochemical hydrotrifluoromethylation of alkynes using the Langlois reagent as a CF3 source. The mild conditions enable broad functional group tolerance and allow late-stage functionalization. Mechanistic studies reveal that DMSO serves a dual role as both solvent and hydrogen atom donor.

키워드

TRIFLUOROMETHYLATIONFLUOROALKYLATIONALKENES
제목
Electrochemical hydrotrifluoromethylation of alkynes
저자
Jang, JihoonCho, Eun Jin
DOI
10.1039/d5cc02370j
발행일
2025-07
유형
Article; Early Access
저널명
Chemical Communications