상세 보기
A novel pH-responsive polysaccharidic ionic complex for proapoptotic D-(KLAKLAK)(2) peptide delivery
- Lee, Bo Reum;
- Oh, Kyung Taek;
- Oh, Young Taik;
- Baik, Hye Jung;
- Park, So Young;
- 외 2명
Citations
WEB OF SCIENCE
39Citations
SCOPUS
41초록
We report charge-switching ionic nanocomplexes comprised of glycol chitosan grafted with 2,3-dimethylmaleic acid (DMA) (denoted as 'GCS-g-DMA' hereafter) and a proapoptotic peptide. This system allowed for improved peptide delivery to tumor sites via a mechanism of selective peptide release when the pH was dropped from 7.4 to 6.8.
키워드
CANCER
- 제목
- A novel pH-responsive polysaccharidic ionic complex for proapoptotic D-(KLAKLAK)(2) peptide delivery
- 저자
- Lee, Bo Reum; Oh, Kyung Taek; Oh, Young Taik; Baik, Hye Jung; Park, So Young; Youn, Yu Seok; Lee, Eun Seong
- 발행일
- 2011-03-15
- 유형
- Article
- 권
- 47
- 호
- 13
- 페이지
- 3852 ~ 3854
- 언어
- ENG
- 출판사
- ROYAL SOC CHEMISTRY
- 발행국가
- 영국
- 분량
- 3 페이지
- ISSN
- P 1359-7345