The East Asian Paradox: An Updated Position Statement on the Challenges to the Current Antithrombotic Strategy in Patients with Cardiovascular Disease

  • Kim, Hyun Kuk; 
  • Tantry, Udaya S.; 
  • Smith, Sidney C., Jr.; 
  • Jeong, Myung Ho; 
  • Park, Seung-Jung; 
  • ... Jeong, Young-Hoon; 
  • 외 19명
Citations

WEB OF SCIENCE

319
Citations

SCOPUS

316

초록

East Asian patients have reduced anti-ischemic benefits and increased bleeding risk during antithrombotic therapies compared with Caucasian patients. As potent P2Y (12) receptor inhibitors (e.g., ticagrelor and prasugrel) and direct oral anticoagulants are commonly used in current daily practice, the unique risk-benefit trade-off in East Asians has been a topic of emerging interest. In this article, we propose updated evidence and future directions of antithrombotic treatment in East Asian patients.

키워드

race; antiplatelet therapy; direct oral anticoagulants; ischemic risk; bleeding risk; PERCUTANEOUS CORONARY INTERVENTION; CLOPIDOGREL PLATELET REACTIVITY; EXPERT CONSENSUS STATEMENT; DUAL ANTIPLATELET THERAPY; CAROTID-ARTERY-DISEASE; ATRIAL-FIBRILLATION; RACIAL-DIFFERENCES; CLINICAL-OUTCOMES; STENT THROMBOSIS; MYOCARDIAL-INFARCTION
제목
The East Asian Paradox: An Updated Position Statement on the Challenges to the Current Antithrombotic Strategy in Patients with Cardiovascular Disease
저자
Kim, Hyun Kuk; Tantry, Udaya S.; Smith, Sidney C., Jr.; Jeong, Myung Ho; Park, Seung-Jung; Kim, Moo Hyun; Lim, Do-Sun; Shin, Eun-Seok; Park, Duk-Woo; Huo, Yong; Chen, Shao-Liang; Bo, Zheng; Goto, Shinya; Kimura, Takeshi; Yasuda, Satoshi; Chen, Wen-Jone; Chan, Mark; Aradi, Daniel; Geisler, Tobias; Gorog, Diana A.; Sibbing, Dirk; Lip, Gregory Y. H.; Angiolillo, Dominick J.; Gurbel, Paul A.; Jeong, Young-Hoon
DOI
10.1055/s-0040-1718729
발행일
2021-04
유형
Review
저널명
Thrombosis and Haemostasis
권
121
호
04
페이지
422 ~ 432