Microfluidic systems for high throughput screening

초록

High-throughput screening (HITS) is a method of scientific experimentation widely used in drug discovery and relevant to the fields of biology and chemistry. Microfluidic systems manipulate or process tiny volumes of fluids in channel with dimensions of tens to hundreds of micrometers and are well suited for HTS due to their small size, which allows massively parallel experimentation. The unique feature of fluids within microfluidic networks can give an insight on new way to resolve the current challenges of HITS and to revolutionize all stages in drug discovery. Herein, recent progress in both microarraying strategies based on microfluidics and novel microfluidic devices with high throughput rates will be discussed.

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