Facile Preparation of Aryl Nitriles from Aryl Aldehydes in PEG-DME 250

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초록

A facile and efficient method is reported for the one-pot transformation of aryl aldehydes to aryl nitriles using hydroxylamine hydrochloride and phosphorus tribromide in PEGDME 250. The conversion of various aryl aldehydes to the corresponding aryl nitriles occurred smoothly in high yields under the present reaction conditions.

키워드

AldehydesaldoximenitrilesphosphoruspolyethylenepolyglymeONE-POT SYNTHESISHIGHLY EFFICIENTUSEFUL REAGENTIONIC LIQUIDCONVERSIONALDOXIMESCATALYSTAMIDESMILDDEHYDRATION
제목
Facile Preparation of Aryl Nitriles from Aryl Aldehydes in PEG-DME 250
저자
Kang, SolbeLee, Jong Chan
DOI
10.2174/1570178618666210909103040
발행일
2022-01
유형
Article
저널명
Letters in Organic Chemistry
19
4
페이지
258 ~ 261