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Optimizing aromatic oligoamide foldamer side-chains for ribosomal translation initiation
- Tsiamantas, Christos;
- Kwon, Sunbum;
- Douat, Celine;
- Huc, Ivan;
- Suga, Hiroaki
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28초록
The tolerance of ribosomal peptide translation for helical aromatic oligoamide foldamers appended as initiators has been investigated. Small cationic foldamer side-chains were shown to expand the range of foldamer-peptide hybrids that can be produced by the ribosome to more rigid sequences.
키워드
CYCLIC-PEPTIDES; N-METHYLATION; GENETIC-CODE; PERMEABILITY; ELONGATION; DISCOVERY; WATER
- 제목
- Optimizing aromatic oligoamide foldamer side-chains for ribosomal translation initiation
- 저자
- Tsiamantas, Christos; Kwon, Sunbum; Douat, Celine; Huc, Ivan; Suga, Hiroaki
- 발행일
- 2019-06
- 유형
- Article
- 권
- 55
- 호
- 51
- 페이지
- 7366 ~ 7369
- 언어
- ENG
- 출판사
- ROYAL SOC CHEMISTRY
- 발행국가
- 영국
- 분량
- 4 페이지
- ISSN
- E 1364-548X
P 1359-7345