Synthesis of 2'-Hydroxydihydrochalcone from Flavone

  • 김미향; 
  • 신복규; 
  • 원동호; 
  • 한재홍

초록

To establish the synthetic method for dihydrochalcones as an important bioactive compounds, 2'-hydroxydihydrochalcone has been synthesized from the reduction of flavone in 20% yield. Flavone with five equivalents of ammonium formate in the presence of Pd/C in methanol under N 2 atmosphere produced the C-ring opened product. It was characterized by UV-VIS, ESI-MS and 1 H−NMR spectroscopy, and identified as 2'-hydroxydihydrochalcone.

키워드

flavone; flavonoids; 2'-hydroxydihydrochalcone; Pd/C; reduction
제목
Synthesis of 2'-Hydroxydihydrochalcone from Flavone
저자
김미향; 신복규; 원동호; 한재홍
발행일
2007
저널명
Journal of Applied Biological Chemistry
권
50
호
2
페이지
85 ~ 87