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Rabies Virus-Inspired Silica-Coated Gold Nanorods as a Photothermal Therapeutic Platform for Treating Brain Tumors
- Lee, Changkyu;
- Hwang, Ha Shin;
- Lee, Sungin;
- Kim, Bomi;
- Kim, Jong Oh;
- ... Oh, Kyung Taek;
- 외 3명
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241초록
Rabies virus-inspired silica-coated gold nanorods are fabricated by mimicking size, shape, surface glycoprotein property and in vivo behavior of the rabies virus. These nanorods not only resemble the appearance of the actual rabies virus but also travel into the brain through the neuronal pathway bypassing the bloodbrain barrier, and moreover respond to near-infrared laser (808 nm) irradiation, emit heat, and effectively suppress brain tumors.
키워드
brain tumors; gold nanorods; localized surface plasmon resonance; photothermal therapy; rabies virus; DRUG-DELIVERY; CELLULAR UPTAKE; GENE DELIVERY; NANOPARTICLES; SHAPE; CELLS; SIZE; MECHANISMS; PARTICLES; CONJUGATE
- 제목
- Rabies Virus-Inspired Silica-Coated Gold Nanorods as a Photothermal Therapeutic Platform for Treating Brain Tumors
- 저자
- Lee, Changkyu; Hwang, Ha Shin; Lee, Sungin; Kim, Bomi; Kim, Jong Oh; Oh, Kyung Taek; Lee, Eun Seong; Choi, Han-Gon; Youn, Yu Seok
- 발행일
- 2017-04
- 유형
- Article
- 권
- 29
- 호
- 13
- 언어
- ENG
- 출판사
- WILEY-V C H VERLAG GMBH
- 발행국가
- 독일
- ISSN
- E 1521-4095
P 0935-9648