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An electrochemical biosensor for detection of the sepsis-related biomarker procalcitonin
- Lim, Jong Min;
- Ryu, Myung Yi;
- Kim, Ji Hong;
- Cho, Chae Hwan;
- Park, Tae Jung;
- ... Park, Jong Pil
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49초록
An electrochemical peptide sensor employing a sensitive synthetic peptide was designed for the diagnosis of sepsis. A series of synthetic peptides were chemically synthesized, and the binding events and performance of the sensor were monitored by CV and EIS. PCT BP3, selected as a potential high-affinity peptide, was found to have a K-d value of 0.39 +/- 0.11 nM for procalcitonin.
키워드
CRITICALLY-ILL PATIENTS; AFFINITY PEPTIDES; METAANALYSIS; PREDICTION; DIAGNOSIS; CARE
- 제목
- An electrochemical biosensor for detection of the sepsis-related biomarker procalcitonin
- 저자
- Lim, Jong Min; Ryu, Myung Yi; Kim, Ji Hong; Cho, Chae Hwan; Park, Tae Jung; Park, Jong Pil
- 발행일
- 2017-07
- 유형
- Article
- 저널명
- RSC Advances
- 권
- 7
- 호
- 58
- 페이지
- 36562 ~ 36565
- 언어
- ENG
- 출판사
- ROYAL SOC CHEMISTRY
- 발행국가
- 영국
- 분량
- 4 페이지
- ISSN
- P 2046-2069