Anti-oxidant activity of avicularin and isovitexin from Lespedeza cuneata

  • Lee, Ju Sung; 
  • Lee, Ah Young; 
  • Quilantang, Norman G.; 
  • Geraldino, Paul John L.; 
  • Cho, Eun Ju; 
  • ... Lee, Sanghyun
Citations

SCOPUS

21

초록

This study evaluated the anti-oxidant activity of avicularin and isovitexin from Lespedeza cuneata using 2,2-diphenyl-1picrylhydrazyl (DPPH) and hydroxyl (OH) scavenging assays. The results showed that among the four fractions, the highest OH radical scavenging activity was exhibited by the n-butanol fraction. The DPPH radical scavenging activities of avicularin and isovitexin were higher than 50% at a concentration of 100 μg/mL. Moreover, one hundred micrograms per liter of avicularin and isovitexin exhibited effective anti-oxidant activity, with the OH radical scavenging rates being 87.54 and 91.48%, respectively. These results suggest that Lespedeza cuneata would be useful anti-oxidant agents from natural sources.

키워드

Avicularin; High performance liquid chromatography; Isovitexin; Lespedeza cuneata; Radical scavenging activity
제목
Anti-oxidant activity of avicularin and isovitexin from Lespedeza cuneata
저자
Lee, Ju Sung; Lee, Ah Young; Quilantang, Norman G.; Geraldino, Paul John L.; Cho, Eun Ju; Lee, Sanghyun
DOI
10.3839/jabc.2019.020
발행일
2019-06
저널명
Journal of Applied Biological Chemistry
권
62
호
2
페이지
143 ~ 147

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