Comparative study of healing fractured tibia assembled with various composite bone plates

초록

This study introduces innovative hybrid-type (Magnesium wire/poly-lactic acid–glass/polypropylene composite (Mg/PLA–Twintex[0]2nT) and bio glass fibers/poly-lactic acid–glass/polypropylene composite (BGF/PLA–Twintex[0]2nT)) partially biodegradable composites for comparison with conventional metallic stainless steel (SS) and fully biodegradable composite bone plates (i.e. Mg/PLA and BGF/PLA), as well as for analyzing their effect towards the healing of fractured healthy and diseased bones. Two different diffusion coefficients are introduced as the biological parameter (0.01 and 0.04 mm2/day) to mimic the blood supply of the diseased and healthy bones. The time-dependent tainted mechanical properties of the degradable composites are implemented to the degradable parts of the bone plates. As hypothesised, we found stress alleviations of 72.36%, 58.82%, 64.82%, and 59.71% in the screws with the diseased bones and alleviations of 84.64%, 72.67%, 77.26%, and 70.8% with the healthy bones in the BGF/PLA, Mg/PLA, BGF/PLA–Twintex[0]2nT, and Mg/PLA–Twintex[0]2nT composite bone plates, respectively. These results were then compared with those for the SS plates on the 28th day of healing. The maximum healing performance was predicted for the hybrid composites as opposed to the degradable and SS implants, thereby confirming the superiority of the proposed composites. © 2020 Elsevier Ltd

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