Simultaneous immunoassay for the detection of two lung cancer markers using functionalized SERS nanoprobes

  • Chon, Hyangah; 
  • Lee, Sangyeop; 
  • Yoon, Soo-Young; 
  • Chang, Soo-Ik; 
  • Lim, Dong Woo; 
  • ... Choo, Jaebum
Citations

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초록

A quick and reproducible SERS-based immunoassay, using functionalized hollow gold nanospheres and magnetic beads, has been developed. Here, a simultaneous detection of dual cancer markers in blood serum has been achieved under a single excitation wavelength. The accuracy and sensitivity for clinical sera from five patients confirms their diagnostic feasibility.

키워드

ENHANCED RAMAN-SCATTERING; GOLD NANOSPHERES; NANOPARTICLES; MICROARRAY; PROTEINS; ANTIBODY; LABELS; BEADS; CHIP
제목
Simultaneous immunoassay for the detection of two lung cancer markers using functionalized SERS nanoprobes
저자
Chon, Hyangah; Lee, Sangyeop; Yoon, Soo-Young; Chang, Soo-Ik; Lim, Dong Woo; Choo, Jaebum
DOI
10.1039/c1cc15707h
발행일
2011-12
유형
Article
저널명
Chemical Communications
권
47
호
46
페이지
12515 ~ 12517