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The improvement of learning and memory ability of normal persons by BF-7
- Lee, Sang Hyung;
- Kim, Yong Sik;
- Kang, Yong Koo;
- Kwon, Oh Sang;
- Shin, Yong Kyoo;
- ... Song, Jin Ho;
- ... Lee, Moo Yeol;
- ... Lee, Tae Jin;
- 외 4명
SCOPUS
9초록
To investigate whether BF-7, extracted from Bombyx mori, improved learning and memory of ordinary people, Rey-Kim Memory Test was performed with placebo group (32 persons), 200 mg BF-7 treated group (33 persons) and 400 mg BF-7 treated group (34 persons). BF-7 enhanced significantly learning and memory function in a dose-dependent manner. To know how BF-7 plays such a positive role, we measured the concentration of acetylcholine in the brain from memory impairment animal model. Treatment of BF-7 significantly increased the concentration of acetylcholine. So, it is supposed that the protection of cholinergic neuron and/or keeping proper concentration of acetylcholine might be one of the mechanisms by which BF-7 improve brain function. So, our results suggest that the BF-7 is effective material for improving learning and memory ability.
키워드
- 제목
- The improvement of learning and memory ability of normal persons by BF-7
- 저자
- Lee, Sang Hyung; Kim, Yong Sik; Kang, Yong Koo; Kwon, Oh Sang; Shin, Yong Kyoo; Song, Jin Ho; Lee, Moo Yeol; Lee, Kwang-Gil; Yeo, Joo-Hong; Lee, Won Bok; Lee, Tae Jin; Kim, Sung Su
- 발행일
- 2004-12
- 유형
- Article
- 권
- 8
- 호
- 6
- 페이지
- 307 ~ 312
- 언어
- ENG
- 출판사
- 대한약리학회
- 발행국가
- 대한민국
- 분량
- 6 페이지
- ISSN
- E 2093-3827
P 1226-4512