Synthesis of fluoroalkylated alkynes via visible-light photocatalysis

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초록

Fluoroalkylated alkynes, which are versatile building blocks for the synthesis of various biologically active organofluorine compounds, were synthesized from easily available alkynyl halides and fluoroalkyl halides by visible-light photocatalysis. Addition of fluoroalkyl radicals to alkynes and subsequent dehalogenation selectively yielded fluoroalkylated alkynes.

키워드

PERFLUOROALKYL IODIDES; CARBOXYLIC-ACIDS; TERMINAL ALKYNES; TRIFLUOROMETHYLATION; FLUORINE; DIFLUOROALKYLATION
제목
Synthesis of fluoroalkylated alkynes via visible-light photocatalysis
저자
Iqbal, Naila; Iqbal, Naeem; Han, Sung Su; Cho, Eun Jin
DOI
10.1039/c8ob02486c
발행일
2019-02
유형
Article
저널명
Organic & Biomolecular Chemistry
권
17
호
7
페이지
1758 ~ 1762