Micro- and nanofluidic systems for high-throughput biological screening

Citations

WEB OF SCIENCE

170
Citations

SCOPUS

200

초록

High-throughput screening (HTS) is a method of scientific experimentation widely used in drug discovery and relevant to the fields Of biology. The development of micro- and nanofluidic systems for use in the biological sciences has been driven by a range of fundamental attributes that accompany miniaturization and massively parallel experimentation. We review recent advances in both arraying strategies based on nano/microfluidics and novel nano/microfluidic devices with high analytical throughput rates.

키워드

DIP-PEN NANOLITHOGRAPHY; CELL-CULTURE ARRAY; MODE WAVE-GUIDES; ON-A-CHIP; SINGLE-MOLECULE SPECTROSCOPY; LARGE-SCALE INTEGRATION; DRUG DISCOVERY; SOFT LITHOGRAPHY; DROPLET MICROFLUIDICS; PROTEIN EXPRESSION
제목
Micro- and nanofluidic systems for high-throughput biological screening
저자
Hong, Jongin; Edel, Joshua B.; deMello, Andrew J.
DOI
10.1016/j.drudis.2008.10.001
발행일
2009-02
유형
Review
저널명
Drug Discovery Today
권
14
호
3-4
페이지
134 ~ 146