Early treatment with inhibitors of P2Y12 receptor in patients with ST-segment elevation myocardial infarction - 2023 ESC recommendations and scientific evidence. Is clinical evidence sufficient to suggest a move towards precision medicine? The ELECTRA-SIRIO 2 investigators' viewpoint

  • Kubica, Jacek
  • Adamski, Piotr
  • Badariene, Jolita
  • Bonaca, Marc
  • Buszman, Piotr
  • ... Jeong, Young-Hoon
  • 외 26명
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초록

The 2023 ESC guidelines changed previously recommended a strategy of early treatment in patients with STEMI. Pre-treatment with a P2Y12 receptor inhibitor may be considered in patients undergoing a primary PCI strategy (Class IIb, Level of evidence B). However, the available scientific evidence justifies a personalized approach differentiating the indications for pre-treatment with oral P2Y12 receptor inhibitors depending on the concomitant administration of opioids. In our opinion, in patients undergoing primary PCI not treated with opioids, pre-treatment with an oral P2Y12 receptor inhibitor should be applied, while in patients undergoing primary PCI treated with opioids, pre-treatment with an oral P2Y12 receptor inhibitor should be considered.

키워드

ACSESC guidelinesP2Y12STEMIpretreatmentCLOPIDOGRELTICAGRELORMORPHINE
제목
Early treatment with inhibitors of P2Y12 receptor in patients with ST-segment elevation myocardial infarction - 2023 ESC recommendations and scientific evidence. Is clinical evidence sufficient to suggest a move towards precision medicine? The ELECTRA-SIRIO 2 investigators' viewpoint
저자
Kubica, JacekAdamski, PiotrBadariene, JolitaBonaca, MarcBuszman, PiotrGabulova, RahimaGajda, RobertGeisler, TobiasGil, RobertGorog, Diana AGurbel, Paul AHajdukiewicz, TomaszHudzik, BartoszJames, StefanJeong, Young-HoonKern, AdamKochman, WacławKubica, AldonaKuliczkowski, WiktorMagielski, PrzemysławNiezgoda, PiotrOstrowska, MałgorzataRaggi, PaoloRahimov, UzeyirSkonieczny, GrzegorzSiller-Matula, Jolanta MSpecchia, GiuseppeSzarpak, ŁukaszSzymański, PawełTantry, UdayaUmińska, JuliaNavarese, Eliano Pio
DOI
10.5603/cj.99973
발행일
2025-03
유형
Review; Early Access
저널명
Cardiology Journal
32
2
페이지
189 ~ 194

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