Early treatment with inhibitors of P2Y12 receptor in patients with ST-segment elevation myocardial infarction - 2023 ESC recommendations and scientific evidence. Is clinical evidence sufficient to suggest a move towards precision medicine? The ELECTRA-SIRIO 2 investigators' viewpoint

  • Kubica, Jacek; 
  • Adamski, Piotr; 
  • Badariene, Jolita; 
  • Bonaca, Marc; 
  • Buszman, Piotr; 
  • ... Jeong, Young-Hoon; 
  • 외 26명
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SCOPUS

1

초록

The 2023 ESC guidelines changed previously recommended a strategy of early treatment in patients with STEMI. Pre-treatment with a P2Y12 receptor inhibitor may be considered in patients undergoing a primary PCI strategy (Class IIb, Level of evidence B). However, the available scientific evidence justifies a personalized approach differentiating the indications for pre-treatment with oral P2Y12 receptor inhibitors depending on the concomitant administration of opioids. In our opinion, in patients undergoing primary PCI not treated with opioids, pre-treatment with an oral P2Y12 receptor inhibitor should be applied, while in patients undergoing primary PCI treated with opioids, pre-treatment with an oral P2Y12 receptor inhibitor should be considered.

키워드

ACS; ESC guidelines; P2Y12; STEMI; pretreatment; CLOPIDOGREL; TICAGRELOR; MORPHINE
제목
Early treatment with inhibitors of P2Y12 receptor in patients with ST-segment elevation myocardial infarction - 2023 ESC recommendations and scientific evidence. Is clinical evidence sufficient to suggest a move towards precision medicine? The ELECTRA-SIRIO 2 investigators' viewpoint
저자
Kubica, Jacek; Adamski, Piotr; Badariene, Jolita; Bonaca, Marc; Buszman, Piotr; Gabulova, Rahima; Gajda, Robert; Geisler, Tobias; Gil, Robert; Gorog, Diana A; Gurbel, Paul A; Hajdukiewicz, Tomasz; Hudzik, Bartosz; James, Stefan; Jeong, Young-Hoon; Kern, Adam; Kochman, Wacław; Kubica, Aldona; Kuliczkowski, Wiktor; Magielski, Przemysław; Niezgoda, Piotr; Ostrowska, Małgorzata; Raggi, Paolo; Rahimov, Uzeyir; Skonieczny, Grzegorz; Siller-Matula, Jolanta M; Specchia, Giuseppe; Szarpak, Łukasz; Szymański, Paweł; Tantry, Udaya; Umińska, Julia; Navarese, Eliano Pio
DOI
10.5603/cj.99973
발행일
2025-03
유형
Review; Early Access
저널명
Cardiology Journal
권
32
호
2
페이지
189 ~ 194

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