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A silicon nanowire platform for drug respnose of captured bt20 cells and evaluation of circulating tumor cells from breast cancer patient's blood
- Kim, D.J.;
- Kim, T.;
- Lee, S.K.
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0초록
Research on specific drug response of circulating tumor cells provides very important information for treatment of cancer patients at a patient-specific level. Consequently, platform for high capture efficiency of CTCs are essential for clinical evaluation of patient-specific drug response of CTCs. In this study, the BT20 cells with an ultra-low abundance range were captured by STR-SiNW platform with high capture efficiency. Specific drug responses of target cells captured on STR-SiNW platforms were analyzed using tamoxifen or docetaxel. In addition, CTCs were successfully captured and evaluated their size distribution from the blood of breast cancer patient. © 15CBMS-0001.
키워드
Breast cancer patient; Circulating Tumor Cells; Drug response; Silicon nanowire arrays; Blood; Cytology; Diseases; Efficiency; Nanowires; Patient treatment; Tumors; Breast Cancer; Capture efficiency; Circulating tumor cells; Clinical evaluation; Drug response; Patient specific; Silicon nanowire arrays; Silicon nanowires; Cells
- 제목
- A silicon nanowire platform for drug respnose of captured bt20 cells and evaluation of circulating tumor cells from breast cancer patient's blood
- 저자
- Kim, D.J.; Kim, T.; Lee, S.K.
- 발행일
- 2015-10
- 유형
- Conference Paper
- 저널명
- MicroTAS 2015 - 19th International Conference on Miniaturized Systems for Chemistry and Life Sciences
- 페이지
- 446 ~ 448
- 언어
- ENG
- 출판사
- Chemical and Biological Microsystems Society
- 분량
- 3 페이지
- ISSN
- P 0000-0000