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Determination of silymarin and silybin diastereomers in korean milk thistle using hplc/uv analysis
HPLC 분석을 통한 한국산 밀크씨슬 중 실리마린과 실리빈의 정량
- Kim, J.;
- Paje, L.A.;
- Choi, J.W.;
- Lee, H.-D.;
- Shim, J.S.;
- ... Lee, S.;
- 외 2명
Citations
SCOPUS
7초록
Silymarin (SM) and silybin diastereomers (SD) in milk thistle (Silybum marianum) were determined using highperformance liquid chromatography and quantified using a reverse-phase column in a gradient elution system. UV detection was performed at 288 nm. The content of SM and SD in milk thistle was 3.236 and 0.553 mg/g DW, respectively. Determining the presence and quantifying the content of SM and SD in milk thistle are vital for the pharmaceutical industry to identify optimal sources for developing health supplements or therapeutics. © 2020, Korean Society of Pharmacognosy. All rights reserved.
키워드
HPLC; Silybin diastereomer; Silybum marianum; Silymarin; acetic acid; acetonitrile; isosilybin; plant extract; silibinin; silicristin; silybin marianum extract; silymarin; unclassified drug; antioxidant activity; Article; bioavailability; controlled study; cosmetic industry; drug industry; elution; high performance liquid chromatography; liquid chromatography; nonhuman; plant leaf; retention time; Silybum marianum; temperature; ultraviolet radiation
- 제목
- Determination of silymarin and silybin diastereomers in korean milk thistle using hplc/uv analysis
- 제목 (타언어)
- HPLC 분석을 통한 한국산 밀크씨슬 중 실리마린과 실리빈의 정량
- 저자
- Kim, J.; Paje, L.A.; Choi, J.W.; Lee, H.-D.; Shim, J.S.; Shim, J.; Geraldino, P.J.L.; Lee, S.
- 발행일
- 2020
- 유형
- Article
- 저널명
- 생약학회지
- 권
- 51
- 호
- 4
- 페이지
- 297 ~ 301
- 언어
- KOR
- 출판사
- Korean Society of Pharmacognosy
- 발행국가
- 대한민국
- 분량
- 5 페이지
- ISSN
- P 0253-3073