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Highly sensitive cancer marker detection on gold-patterned microarray chip using surface-enhanced Raman scattering imaging
- Lee M.;
- Lee J.-H.;
- Lim H.-W.;
- Park J.-G.;
- Choo, Jaebum
Citations
SCOPUS
0초록
This paper reports a novel method for the highly sensitive cancer marker detection using a gold-patterned microarray chip and a surface-enhanced Raman scattering imaging (SERSi). In this work, we designed and fabricated a conceptually new gold-patterened glass microarray chip. Here, gold patterned hydrophilic spots are completely isolated from hydrophobic surfaces, and the hydrophobic/hydrophilic hybrid property of the microarrays greatly improves the biomolecule deposition, spot uniformity, replication, and reproducibility. This gold-patterned microarray chp has been successfully used for a highly sensitive cancer marker detection. © 2009 CBMS.
키워드
Hydrophobic pattern; Immunoassay; Microarray; SERS Imaging; Diseases; Gold; Hydrophobicity; Raman scattering; Surface chemistry; Surface scattering; Cancer markers; Hydrophobic patterns; Hydrophobic surfaces; Hydrophobic/hydrophilic; Immunoassay; Micro-array chips; Reproducibilities; Surface enhanced Raman Scattering (SERS); Microarrays
- 제목
- Highly sensitive cancer marker detection on gold-patterned microarray chip using surface-enhanced Raman scattering imaging
- 저자
- Lee M.; Lee J.-H.; Lim H.-W.; Park J.-G.; Choo, Jaebum
- 발행일
- 2009-11
- 유형
- Conference Paper
- 저널명
- Proceedings of Conference, MicroTAS 2009 - The 13th International Conference on Miniaturized Systems for Chemistry and Life Sciences
- 페이지
- 466 ~ 468
- 언어
- ENG
- 출판사
- Chemical and Biological Microsystems Society
- 분량
- 3 페이지
- ISSN
- P 0000-0000