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Patterned Multiplex Pathogen DNA Detection by Au Particle-on-Wire SERS Sensor
- Kang, Taejoon;
- Yoo, Seung Min;
- Yoon, Ilsun;
- Lee, Sang Yup;
- Kim, Bongsoo
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370초록
A Au particle-on-wire system that can be used as a specific, sensitive, and multiplex DNA sensor is developed. A pattern formed by multiple Au nanowire sensors provides positional address and identification for each sensor. By using this system, multiplex sensing of target DNAs was possible in a quantitative manner with a detection limit of 10 pM. Target DNAs from reference bacteria and clinical isolates were successfully identified by this sensor system, enabling diagnostics for infectious diseases.
키워드
DNA; multiplex; pathogen; pattern; surface-enhanced Raman scattering; ENHANCED RAMAN-SCATTERING; REMOTE-EXCITATION; SILVER NANOWIRE; SINGLE-NANOWIRE; HOT-SPOTS; SPECTROSCOPY; NANOPARTICLES; HYBRIDIZATION; MOLECULES; SURFACES
- 제목
- Patterned Multiplex Pathogen DNA Detection by Au Particle-on-Wire SERS Sensor
- 저자
- Kang, Taejoon; Yoo, Seung Min; Yoon, Ilsun; Lee, Sang Yup; Kim, Bongsoo
- 발행일
- 2010-04
- 유형
- Article
- 저널명
- Nano Letters
- 권
- 10
- 호
- 4
- 페이지
- 1189 ~ 1193
- 언어
- ENG
- 출판사
- AMER CHEMICAL SOC
- 발행국가
- 미국
- 분량
- 5 페이지
- ISSN
- E 1530-6992
P 1530-6984