Immunohistochemical study on the distribution of TRPC channels in the rat hippocampus

Chung, Yoon Hee; Ahn, Hyang Sun; Kim, Daejin; Shin, Dong Hoon; Kim, Sung Su; Kim, Kyung Yong; Lee, Won Bok; Cha, Choong Ik

doi:10.1016/j.brainres.2006.02.087

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Immunohistochemical study on the distribution of TRPC channels in the rat hippocampus

Chung, Yoon Hee;
Ahn, Hyang Sun;
Kim, Daejin;
Shin, Dong Hoon;
Kim, Sung Su;
... Kim, Kyung Yong;
외 2명

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70

초록

In the present study, we performed immunohistochemistry using antibodies directed against TRPCs to study the localizations of these channels in rat hippocampus. The pyramidal cell bodies of CA1-3 areas and the granule cell bodies of the dentate gyrus were immunoreactive for TRPC1, TRPC3, TRPC4 and TRPC5. On the other hand, TRPC6 exhibited the cloud-like neuropil staining only in the molecular layer of the dentate gyrus. As a whole, the present study has clearly shown the localization of TRPCs in rat hippocampus and may provide useful data for the future investigations on the structural and functional properties of TRPCs. (c) 2006 Elsevier B.V. All rights reserved.

키워드

transient receptor potential (TRP); channel; TRPC; rat; hippocampus; immunohistochemistry; CATION CHANNEL; GROWTH CONES; BRAIN; AMYGDALA; MEMORY; CELLS

제목: Immunohistochemical study on the distribution of TRPC channels in the rat hippocampus

저자: Chung, Yoon Hee; Ahn, Hyang Sun; Kim, Daejin; Shin, Dong Hoon; Kim, Sung Su; Kim, Kyung Yong; Lee, Won Bok; Cha, Choong Ik

DOI: 10.1016/j.brainres.2006.02.087

발행일: 2006-04

유형: Article

저널명: Brain Research

권: 1085

호: 1

페이지: 132 ~ 137

언어: ENG

출판사: ELSEVIER SCIENCE BV

발행국가: 네덜란드

분량: 6 페이지

ISSN: E 1872-6240
P 0006-8993