Microfluidic-Assisted Fabrication of Flexible and Location Traceable Organo-Motor

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초록

In this paper, we fabricate a flexible and location traceable micromotor, called organo-motor, assisted by microfluidic devices and with high throughput. The organo-motors are composed of organic hydrogel material, poly (ethylene glycol) diacrylate (PEGDA), which can provide the flexibility of their structure. For spatial and temporal traceability of the organo-motors under magnetic resonance imaging (MRI), superparamagnetic iron oxide nanoparticles (SPION; Fe3O4) were incorporated into the PEGDA microhydrogels. Furthermore, a thin layer of platinum (Pt) was deposited onto one side of the SPION-PEGDA microhydrogels providing geometrical asymmetry and catalytic propulsion in aqueous fluids containing hydrogen peroxide solution, H2O2 Furthermore, the motion of the organo-motor was controlled by a small external magnet enabled by the presence of SPION in the motor architecture.

키워드

Flexible; hydrogel; magnetic resonance imaging; micromotor; microfluidics; microparticle; organo-motor; poly (ethylene glycol) diacrylate; self-propulsion; superparamagnetic iron oxide nanoparticles; EMULSION SOLVENT EVAPORATION; CATALYTIC NANOMOTORS; AUTONOMOUS MOVEMENT; DRUG-DELIVERY; PARTICLE-SIZE; JANUS; MICROPARTICLES; CARGO; MICROMOTORS; WATER
제목
Microfluidic-Assisted Fabrication of Flexible and Location Traceable Organo-Motor
저자
Seo, Kyoung Duck; Kwak, Byung Kook; Sanchez, Samuel; Kim, Dong Sung
DOI
10.1109/TNB.2015.2402651
발행일
2015-04
유형
Article
저널명
IEEE Transactions on Nanobioscience
권
14
호
3
페이지
298 ~ 304