A Smart Polysaccharide/Drug Conjugate for Photodynamic Therapy

Park, So Young; Baik, Hye Jung; Oh, Young Taik; Oh, Kyung Taek; Youn, Yu Seok; Lee, Eun Seong

doi:10.1002/anie.201006038

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A Smart Polysaccharide/Drug Conjugate for Photodynamic Therapy

Park, So Young;
Baik, Hye Jung;
Oh, Young Taik;
Oh, Kyung Taek;
Youn, Yu Seok;
외 1명

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241

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252

초록

Sharper image: A newly developed polysaccharide/drug conjugate (see picture) responds to changes in pHa value and was shown to penetrate HeLa tumors in mice as determined by fluorescence imaging. It has the potential to be used in photodynamic therapy, thereby targeting the tumor while having no detrimental effects on the surrounding tissue. © 2011 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

키워드

drug delivery; imaging agents; photodynamic therapy; polysaccharides; GLYCOL CHITOSAN; IN-VITRO; CANCER; NANOPARTICLES; NANOGEL

제목: A Smart Polysaccharide/Drug Conjugate for Photodynamic Therapy

저자: Park, So Young; Baik, Hye Jung; Oh, Young Taik; Oh, Kyung Taek; Youn, Yu Seok; Lee, Eun Seong

DOI: 10.1002/anie.201006038

발행일: 2011-02-11

유형: Article

저널명: Angewandte Chemie International Edition

권: 50

호: 7

페이지: 1644 ~ 1647

언어: ENG

출판사: WILEY-V C H VERLAG GMBH

발행국가: 독일

분량: 4 페이지

ISSN: E 1521-3773
P 1433-7851