한국형 양극성 장애 약물치료 알고리듬 2014 : 유지치료

초록

Objectives : In this study, we aimed to deal with the recommendations for the maintenance treatment for bipolar disorder in Korean Medication Algorithm Project for Bipolar Disorder (KMAP-BP) 2014. Method : The questionnaire regarding strategies for maintenance treatment was composed of overall treatment strategies after acute mood episodes, choice of antipsychotics and antidepressants, treatment duration and treatment strategies for breakthrough symptoms. Results : Regarding the maintenance treatment after acute hypomanic or manic episode in bipolar I or II disorder, combination therapy of mood stabilizer and an atypical antipsychotic agent, monotherapy of mood stabilizer and monotherapy of an atypical antipsychotic agent were chosen as 1st-line treatment. Regarding the maintenance treatment after depressive episode in bipolar I or II disorder, combination therapy of mood stabilizer and an atypical antipsychotic agent, combination of mood stabilizer and lamotrigine, combination of an atypical antipsychotic agent and lamotrigine, mood stabilizer monotherapy, lamotrigine monotherapy, and atypical antipsychotic agent monotherapy were chosen as 1st-line treatment. Preference for atypical antipsychotics and antide-pressants became increased in KMAP-BP 2014 compared to KMAP-BP 2010. Conclusion : The recommendations for the maintenance treatment in KMAP-BP 2014 seem to reflect current changes in prescription pattern for bipolar disorder.

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