General anesthesia versus sedation with dexmedetomidine for thoracic endovascular aortic repair in 38 patients in multicenter experiences: A retrospective study

초록

Background: Endovascular stent graft placement is a usefultreatment option in lesions of the thoracic aorta. The aim of thisstudy was to assess the possibility of sedation with dexmedetomidinecompared with general anesthesia in patients undergoing thoracicendovascular aortic repair (TEVAR) in a multi-center clinical trial. Methods: Data from 38 patients with thoracic aorta lesions treatedby TEVAR between April 2010 and November 2013 wereretrospectively collected at two hospitals. General anesthesia orsedation with dexmedetomidine was determined according to thehospital. Demographics, anesthetic recordings, and complicationswere reviewed. Results: Stent graft placement was technically successful in allpatients. There were no events during the anesthetic period. Atotal of 38 patients underwent TEVAR; 29 patients received generalanesthesia, and 9 received sedation. Dexmedetomidine sedation(loading dose: 0.5–1.0 g/kg for 10 min, maintenance: 0.2–0.8g/kg/h) was successfully performed without anesthesia-relatedcomplications or mortality. During the procedure, mean arterialpressure, heart rate, and saturation of peripheral oxygen were notstatistically different between general anesthesia anddexmedetomidine sedation. Conclusions: In our study, TEVAR under sedation with dexmedetomidinewas shown to be a feasible procedure that was welltolerated without specific complications.

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