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Antidepressants for neuro-regeneration: from depression to Alzheimer's disease
- Kim, Hyun-Jung;
- Kim, Woosuk;
- Kong, Sun-Young
Citations
WEB OF SCIENCE
30Citations
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33초록
Recently identified new potential functions of antidepressants in the treatment of neurodegenerative will be introduced. Antidepressants are reported to regulate stem cell fate to regenerate neurons in the adult hippocampus and are effective in reducing toxic amyloid peptides and are known to increase neurotrophic factor such as brain-derived neurotrophic factor. Clinical trial data support that antidepressants have potential to treat Alzheimer's disease.
키워드
Antidepressants; Neurogenesis; Alzheimer's disease; Brain derived neurotrophic factor; Depression; CHRONIC MILD STRESS; LIPOPOLYSACCHARIDE-INDUCED APOPTOSIS; CHRONIC FLUOXETINE TREATMENT; HIPPOCAMPAL NEUROGENESIS; DOUBLE-BLIND; NEUROTROPHIC FACTOR; CELL-PROLIFERATION; STEM-CELLS; HUNTINGTONS-DISEASE; PARKINSONS-DISEASE
- 제목
- Antidepressants for neuro-regeneration: from depression to Alzheimer's disease
- 저자
- Kim, Hyun-Jung; Kim, Woosuk; Kong, Sun-Young
- 발행일
- 2013-11
- 유형
- Review
- 권
- 36
- 호
- 11
- 페이지
- 1279 ~ 1290
- 언어
- ENG
- 출판사
- PHARMACEUTICAL SOC KOREA
- 발행국가
- 대한민국
- 분량
- 12 페이지
- ISSN
- E 1976-3786
P 0253-6269