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- Ji Yeon Choi;
- 김혜민;
- 목소연;
- 최경;
- 구자정;
- ... 이상현;
- 외 2명
초록
The aim of this research was to investigate the industrial application of Sedum sarmentosum. Antibacterial activities of the n-hexane, methylene chloride (MC), ethyl acetate, and n-butanol fractions of S. sarmentosum were tested against Escherichia coli,Staphylococcus aureus, and Helicobacter pylori. The MC fraction showed the strongest antibacterial activity against E. coli, with an inhibition zone greater than 13 mm in disc assays. At 100 μg/mL,all fractions scavenged more than 50% of 1,1-diphenyl-2-picrylhydrazyl (DPPH) and hydroxyl radicals (·OH). In particular,the MC fraction showed the strongest scavenging activity against DPPH and ·OH. In addition, we found that treatment with the MC fraction inhibited the growth of H. pylori and gastric adenocarcinoma cells. The present results suggest that the MC fraction of S. sarmentosum would play the promising protective role against pathogenic bacteria and free radicals.
키워드
- 제목
- 돌나물의 항균활성 및 위암예방효과
- 제목 (타언어)
- Antibacterial Activity and Protective Role against Gastric Cancer by Sedum sarmentosum
- 저자
- Ji Yeon Choi; 김혜민; 목소연; 최경; 구자정; 박광우; 조은주; 이상현
- 발행일
- 2012-09
- 권
- 55
- 호
- 3
- 페이지
- 157 ~ 161