Candida 종에 의한 병원-획득성 요로감염에서 위험인자 분석

초록

Background: Although an increase of candiduria among hospitalized patients has been reported, the significance of the presence of Candida spp. in the urine of patients is not clearly understood. Objective: The purpose of this study was to determine the prevalence of Candida spp. in patients with hospital-acquired urinary tract infection (HAUTI) and their risk factors. Methods: Retrospective studies of patients with urinary tract infection were conducted during the period from January 2003 to December 2005. Medical records of patients were reviewed and 185 patients were diagnosed with HAUTI by Candida spp. Results: The predominant species were C. tropicalis (46.5%), followed by C. albicans (29.2%) and C. glabrata (17.3%). The commonest coexisting risk factors in patients with HAUTI by Candida spp. were antibiotic therapy (96.2%) and indwelling urinary catheters (92.4%). Female gender, long hospital day, antifungal therapy and leukocytosis were specifically associated with C. glabrata but not with C. albicans HAUTI. On the other hand, operation history was associated with C. tropicalis but not with C. albicans HAUTI. Conclusion: We demonstrated that the risk factors for HAUTI differ according to Candida species. There is an need for continuous surveillance of HAUTI by Candida spp. and proper control of the risk factors for the development of HAUTI.

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