Directed Blood Vessel Growth Using an Angiogenic Microfiber/Microparticle Composite Patch

DeVolder, Rossi J.; Bae, Harim; Lee, Jonghwi; Kong, Hyunjoon

doi:10.1002/adma.201100823

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Directed Blood Vessel Growth Using an Angiogenic Microfiber/Microparticle Composite Patch

DeVolder, Rossi J.;
Bae, Harim;
Lee, Jonghwi;
Kong, Hyunjoon

Citations

WEB OF SCIENCE

38

Citations

SCOPUS

42

초록

An angiogenic microfiber patch that releases angiogenic growth factors along aligned fibers and subsequently directs the spacing and orientation of mature and functional blood vessel formation is presented. The fiber patches are prepared by electrostatically binding electrosprayed vascular endothelial growth factor (VEGF)-encapsulating poly(lactide-co-glycolide) (PLGA) microparticles with electrospun poly(lactide) (PLA) microfibers.

키워드

drug delivery; fibers; microstructures; polymeric materials; tissue engineering; NANOFIBERS; MORPHOGENESIS; OPPORTUNITIES; MICROFIBERS; MEDICINE; MATRICES; CELLS; VEGF

제목: Directed Blood Vessel Growth Using an Angiogenic Microfiber/Microparticle Composite Patch

저자: DeVolder, Rossi J.; Bae, Harim; Lee, Jonghwi; Kong, Hyunjoon

DOI: 10.1002/adma.201100823

발행일: 2011-07-26

유형: Article

저널명: Advanced Materials

권: 23

호: 28

페이지: 3139 ~ +

언어: ENG

출판사: WILEY-BLACKWELL

발행국가: 독일

ISSN: E 1521-4095
P 0935-9648