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초록
Chromatographic separation of the 80% MeOH extract of the leaves of Ilex rotunda (IR) led to isolation of two new hemiterpene glycosides, tentatively named as rotundarpenoside A (1) and rotundarpenoside B (2), along with five known caffeoyl derivatives (3-7). The chemical structures of these compounds were elucidated using 1D/2D NMR, HR-MS, and the absolute configuration was confirmed by Mosher's method. In order to evaluate their anti-oxidative activities, 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical scavenging activity and xanthine oxidase superoxide scavenging activities (NBT) were determined.
키워드
Ilex rotunda; Hemiterpenes; Caffeoylquinic acids; Anti-oxidative activity; ACID-DERIVATIVES; QUINIC ACID; CONSTITUENTS; TRITERPENES
- 제목
- Two new hemiterpene glycosides from the leaves of Ilex rotunda. thunb
- 저자
- Kim, Manh Heun; Park, Kwan Hee; Oh, Myeong Hwan; Kim, Han Hyuk; Choe, Kang In; Park, Sang Hee; Lee, Min Won
- 발행일
- 2012-10
- 유형
- Article
- 권
- 35
- 호
- 10
- 페이지
- 1779 ~ 1784