Serum MRGPRX2 as a Long-term Biomarker for Iodinated Contrast Media-Induced Anaphylaxis

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초록

Departments the curve of 0.61 ( P = 0.058). When groups were classified based on the time interval, T1(0-2months) and T2 (2-4months), patients with anaphylaxis had higher MRGPRX2 levels compared to the non -anaphylaxis group in the T2 group (36.5 +/- 19.2 vs. 20.5 +/- 19.0, P = 0.035). This pilot study shows that serum MRGPRX2 is a potential long-term biomarker for predicting anaphylaxis, particularly ICM-induced anaphylaxis. Further studies are needed to determine the role of MRGPRX2 in anaphylaxis in a larger population of patients with various drug -induced IHRs.

키워드

Hypersensitivity; drug; anaphylaxis; tryptase; HYPERSENSITIVITY REACTIONS; DIAGNOSIS
제목
Serum MRGPRX2 as a Long-term Biomarker for Iodinated Contrast Media-Induced Anaphylaxis
저자
An, Jin; Lee, Chea Eun; Kim, Seo-Young; Park, So -Young; Kim, Sujeong; Sim, Da Woon; Yang, Min-Suk; Park, Han-Ki; Kim, Sae-Hoon; Kim, Sang-Heon; Ye, Young -Min; Lee, Jae Hyun; Hur, Gyu Young; Park, Hye-Kyung; Koh, Youngil; Park, Jung-Won; Lee, Jaechun; Lee, Byung-Jae; Kim, Tae-Bum
DOI
10.4168/aair.2024.16.3.308
발행일
2024-05
유형
Article
저널명
Allergy, Asthma & Immunology Research
권
16
호
3
페이지
308 ~ 316