Synthesis of α,ω-dicarboxylic acid dimethyl esters from cycloalkanones

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초록

Reaction of cycloalkanones with [hydroxy(2,4-dinitrobenzenesulfonyloxy)iodo] benzene and subsequent treatment of alpha-[(2,4-dinitrobenzene)sulfonyl]oxy cycloalkanone intermediates with Oxone((C)) and PTSA in MeOH-H2O (6:1, v/v) solution provided dicarboxylic acid dimethyl esters in high yields.

키워드

carboxylic acidsestersketonesoxidationsring openingENOL SILYL ETHERSALPHA-NITROKETONESKETONESCONVERSIONCLEAVAGE
제목
Synthesis of α,ω-dicarboxylic acid dimethyl esters from cycloalkanones
저자
Lee, Jong ChanKu, Chang Hoe
DOI
10.1055/s-2002-34236
발행일
2002-10
유형
Article
저널명
Synlett
10
페이지
1679 ~ 1680