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Regulation of Neural Stem Cell Fate by Natural Products
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8초록
Neural stem cells (NSCs) can proliferate and differentiate into multiple cell types that constitute the nervous system. NSCs can be derived from developing fetuses, embryonic stem cells, or induced pluripotent stem cells. NSCs provide a good platform to screen drugs for neurodegenerative diseases and also have potential applications in regenerative medicine. Natural products have long been used as compounds to develop new drugs. In this review, natural products that control NSC fate and induce their differentiation into neurons or glia are discussed. These phytochemicals enable promising advances to be made in the treatment of neurodegenerative diseases.
키워드
Neural stem cells; Cell fate; Neurogenesis; Differentiation; Antioxidative; Neuroprotection; MIDBRAIN DOPAMINERGIC-NEURONS; CORTEX RADICIS MORACEAE; GINKGO-BILOBA EXTRACT; HIPPOCAMPAL NEUROGENESIS; GINSENOSIDE RG1; SALVIA-MILTIORRHIZA; CHINESE MEDICINE; IN-VIVO; MOLECULAR-MECHANISMS; ADULT NEUROGENESIS
- 제목
- Regulation of Neural Stem Cell Fate by Natural Products
- 저자
- Kim, Hyun-Jung
- 발행일
- 2019-01
- 유형
- Review
- 권
- 27
- 호
- 1
- 페이지
- 15 ~ 24
- 언어
- ENG
- 출판사
- KOREAN SOC APPLIED PHARMACOLOGY
- 발행국가
- 대한민국
- 분량
- 10 페이지
- ISSN
- E 2005-4483
P 1976-9148