Regulation of Neural Stem Cell Fate by Natural Products

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6
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8

초록

Neural stem cells (NSCs) can proliferate and differentiate into multiple cell types that constitute the nervous system. NSCs can be derived from developing fetuses, embryonic stem cells, or induced pluripotent stem cells. NSCs provide a good platform to screen drugs for neurodegenerative diseases and also have potential applications in regenerative medicine. Natural products have long been used as compounds to develop new drugs. In this review, natural products that control NSC fate and induce their differentiation into neurons or glia are discussed. These phytochemicals enable promising advances to be made in the treatment of neurodegenerative diseases.

키워드

Neural stem cells; Cell fate; Neurogenesis; Differentiation; Antioxidative; Neuroprotection; MIDBRAIN DOPAMINERGIC-NEURONS; CORTEX RADICIS MORACEAE; GINKGO-BILOBA EXTRACT; HIPPOCAMPAL NEUROGENESIS; GINSENOSIDE RG1; SALVIA-MILTIORRHIZA; CHINESE MEDICINE; IN-VIVO; MOLECULAR-MECHANISMS; ADULT NEUROGENESIS
제목
Regulation of Neural Stem Cell Fate by Natural Products
저자
Kim, Hyun-Jung
DOI
10.4062/biomolther.2018.184
발행일
2019-01
유형
Review
저널명
Biomolecules & Therapeutics
권
27
호
1
페이지
15 ~ 24

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