Arthroscopic debridement for acutely infected prosthetic knee: Any role for infection control and prosthesis salvage?

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초록

Purpose The purpose of this study was to assess the success rate of arthroscopic debridement guided by C-reactive protein (CRP) levels for acutely infected total knee prostheses. Methods From January 2002 to December 2009, 16 consecutive eligible patients met the following inclusion criteria: duration of symptoms less than 72 hours, previously well-functioning prostheses, and no radiographic signs of loosening. Each patient underwent arthroscopy with thorough debridement and synovectomy and copious irrigation. In addition to the standard anterior portals, a posterior portal was used, and a drain was placed through this portal. The need for subsequent open debridement was determined by the postarthroscopy trends of CRP levels. Treatment success was defined as continuing freedom from infection based on clinical and laboratory results, salvage of the prosthesis, and no evidence of infection for at least 2 years. Results Arthroscopic debridement eradicated the infection in 10 (62.5%) of the 16 cases. The other 6 knees (37.5%) underwent subsequent open debridement with polyethylene insert exchange, which resulted in successful infection control with prosthetic salvage. Conclusions Patients who had undergone total knee arthroplasty (TKA) and had acute joint infection for less than 72 hours with no evidence of a loosening prosthesis were treated by arthroscopic debridement guided by the CRP level and had a 62.5% success rate with arthroscopic treatment alone but a 100% success rate when initial failures were treated with open debridement and polyethylene exchange. Level of Evidence Level IV, case series. © 2014 by the Arthroscopy Association of North America.

키워드

C reactive protein; polyethylene; adult; aged; arthroscopic debridement; article; clinical article; disease duration; drain; female; human; infection control; knee arthroscopy; knee prosthesis; male; medical device complication; nonhuman; prosthesis infection; prosthesis loosening; salvage therapy; symptomatology; synovectomy; total knee replacement; treatment failure; treatment outcome; Aged; Arthroplasty, Replacement, Knee; Arthroscopy; Biological Markers; C-Reactive Protein; Debridement; Equipment Failure Analysis; Female; Humans; Infection Control; Knee Prosthesis; Male; Middle Aged; Prosthesis-Related Infections; Salvage Therapy; Synovial Membrane; Therapeutic Irrigation; Treatment Outcome
제목
Arthroscopic debridement for acutely infected prosthetic knee: Any role for infection control and prosthesis salvage?
저자
Chung, J.Y.; Ha, C.W.; Park, Yong Beom; Song, Y.J.; Yu, K.S.
DOI
10.1016/j.arthro.2014.02.008
발행일
2014-05
유형
Article
저널명
Arthroscopy - Journal of Arthroscopic and Related Surgery
권
30
호
5
페이지
599 ~ 606