Effect of Shift Work on Nocturia

초록

OBJECTIVE To identify the circadian sensitive component of nocturia by comparing nocturia in patients who voluntarily choose a disrupted circadian rhythm, that is, shift workers, with those who maintain normal day-night cycles. MATERIALS AND METHODS Between 2011 and 2013, a total of 1741 untreated patients, 1376 nonshift workers and 365 shift workers, were compared for nocturia indices based on frequency volume charts (FVCs). General linear model of 8-hour interval urine production and frequency were compared between FVCs of nonshift workers, FVCs of night-shift workers, and FVCs of day-shift workers. RESULTS Nocturia frequency was increased in the night-shift workers (2.38 +/- 1.44) compared with nonshift workers (2.18 +/- 1.04) (P <.01). Whereas nocturnal polyuria index did not increase significantly (0.33 +/- 0.19 for night-shift workers, 0.34 +/- 0.13 for nonshift workers, P = .24), nocturnal bladder capacity index increased significantly (1.41 +/- 1.06 for night-shift workers, 1.26 +/- 0.92 for nonshift workers, P <.01). Eight-hour interval indices show that urine production changed with shift (P <.01), whereas voiding frequency remains unchanged despite shift changes (P = .35). CONCLUSION Patients in alternating work shifts showed increased nocturia, especially during their night shift. These changes tended to be more associated with decreased nocturnal bladder capacity than increased nocturnal polyuria. (C) 2015 Elsevier Inc.

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