Expanding Horizons: Unveiling the Clinical Features of Early Gastric Lymphoepithelioma-Like Carcinoma and the Potential of Endoscopic Resection as Curative Therapy

초록

Gastric lymphoepithelioma-like carcinoma (LELC) is a rare form of gastric cancer with distinct clinicopathological features, first systematically reported by Watanabe et al. in 1976.1 Gastric LELC is also referred to as gastric carcinoma with lymphoid stroma, which is characterized by gastric carcinoma composed of small nests of cancer cells with abundant, diffuse lymphocyte infiltration in the stroma that be strongly associated with either Epstein-Barr virus (EBV) infection and microsatellite instability, which are mutually and optimal treatment strategies are not well understood.