Spatial effect of conical angle on optical-thermal distribution for circumferential photocoagulation

  • Van Gia Truong
  • Park, Suhyun
  • Van Nam Tran
  • Kang, Hyun Wook
Citations

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초록

A uniformly diffusing applicator can be advantageous for laser treatment of tubular tissue. The current study investigated various conical angles for diffuser tips as a critical factor for achieving radially uniform light emission. A customized goniometer was employed to characterize the spatial uniformity of the light propagation. An ex vivo model was developed to quantitatively compare die temperature development and irreversible tissue coagulation. The 10-mm diffuser tip with angle at 25 degrees achieved a uniform longitudinal intensity profile (i.e., 0.90 +/- 0.07) as well as a consistent thermal denaturation on die tissue. The proposed conical angle can be instrumental in determining the uniformity of light distribution for die photothermal treatment of tubular tissue. (C) 2017 Optical Society of America

키워드

CYLINDRICAL DIFFUSERPHOTODYNAMIC THERAPYLIGHTPERFORMANCECOAGULATIONDELIVERYFIBERSMODEL
제목
Spatial effect of conical angle on optical-thermal distribution for circumferential photocoagulation
저자
Van Gia TruongPark, SuhyunVan Nam TranKang, Hyun Wook
DOI
10.1364/BOE.8.005663
발행일
2017-12
유형
Article
저널명
Biomedical Optics Express
8
12
페이지
5663 ~ 5674

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