니켈 촉매하에서 Secondary alkyl Grignard 시약을 이용한 Arenesulfonate의 Hydrogenolysis

초록

Neopentyl arenesulfonate react with secondary alkylmagnesium chloride in the presence of Ni(0) catalyst to produce arene compounds via the reductive cleavage of carbon-sulfur bond. Highest yield is obtained by using three equivalents of Grignard reagent to the mixture of arenesulfonate and dppfNiCl2 in Et2O at room temperature. This reaction represents a novel method allowing the efficient hydrogenolysis of sulfur-containing aromatic compounds.