Artificial nano-pin as a temporal molecular glue for the targeting of acidic tumor cells

초록

Highly precise control of molecular structure for developing efficient anticancer drug delivery is challenging. Our method reported herein can satisfy the need for building novel hybrid molecule; this molecule serves as a built-in transformer that changes its molecular configuration from a pin-shaped arrangement to a dog bone-shaped arrangement. This approach led to a significant increase in the efficiency of tumor inhibition. Copyright (C) 2014 John Wiley & Sons, Ltd.

키워드