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Engineered chitosan-xanthan gum biopolymers effectively adhere to cells and readily release incorporated antiseptic molecules in a sustained manner
- Kim, Jieun;
- Hwang, Jangsun;
- Seo, Youngmin;
- Jo, Yeonho;
- Son, Jaewoo;
- ... Choi, Jonghoon
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43초록
The polyelectrolyte complexes that contain anionic xanthan gum and cationic chitosan formed or coalesced into biopolymeric scaffolds. To increase the viscosity and adherent properties of the prepared scaffolds, chitosanxanthan gum microspheres were prepared by coacervation. The coalesced biopolymer was mixed with CHX to form injectable antibacterial hydrogels. We successfully prepared a biocompatible, antiseptic, chitosanxanthan gum-based biopolymer with a potential to be used as an effective local antiseptic for acute or chronic periodontitis. (C) 2016 The Korean Society of Industrial and Engineering Chemistry. Published by Elsevier B.V. All rights reserved.
키워드
Chitosan; Xanthan gum; Chlorohexidine; Biopolymer; Antiseptic agent; DRUG-DELIVERY SYSTEMS; PHARMACEUTICAL APPLICATIONS; POLYELECTROLYTE COMPLEXES; BIOMEDICAL APPLICATIONS; HYDROGELS; CHITIN; DERIVATIVES; IMMOBILIZATION; MATRIX; BIODEGRADATION
- 제목
- Engineered chitosan-xanthan gum biopolymers effectively adhere to cells and readily release incorporated antiseptic molecules in a sustained manner
- 저자
- Kim, Jieun; Hwang, Jangsun; Seo, Youngmin; Jo, Yeonho; Son, Jaewoo; Choi, Jonghoon
- 발행일
- 2017-02
- 유형
- Article
- 권
- 46
- 페이지
- 68 ~ 79
- 언어
- ENG
- 출판사
- ELSEVIER SCIENCE INC
- 발행국가
- 미국
- 분량
- 12 페이지
- ISSN
- E 1876-794X
P 1226-086X