ScholarWorks@중앙대학교

초록

Background: Clinical laboratories in laboratory medicine perform a wide range of clinical chemistry and immunoassay tests, and internal quality control (QC) is an essential element of laboratory operations. This study aimed to improve the inefficiencies associated with using in-kit assay-spe- cific QC materials by consolidating QC materials using third-party universal liquid QC materials. Methods: The study was conducted using Cobas e801, Alinity i, and LABOSPECT 008AS equipment. Universal liquid QC materials for immunoas- says and clinical chemistry tests were selected and their precisions, QC management time, annual costs of reagent and consumables, and storage space requirements were evaluated. Results: Comparison of coefficients of variation (CVs) showed that while assay-specific QC materials had lower CVs for certain tests, universal QC materials exhibited lower CVs for other tests. Consolidation of QC materials reduced their total number by 42.3% and the actual number of QC items managed by 52.0%. QC management time decreased by 50.2%. The annual cost of reagents and consumables was reduced by 8.3%, whereas storage space decreased by 52.1%. Conclusions: Implementation of universal liquid QC materials can enhance the efficiency of clinical laboratories, reduce costs, and provide envi- ronmental benefits. Adoption of universal liquid QC materials is recommended for large laboratories.

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