Efficacy and safety of a home-use multi-energy-based device for skin tightening: a preclinical study

초록

Background: Several studies have investigated the effects of simultaneous application of various energy sources and technologies, such as radio frequencies, light-emitting diodes, and microcurrents, as well as sonophoresis and iontophoresis. The current study aims to develop a safe and effective home-use device that utilizes the synergistic effects of different energies and technologies.Methods: Six pigs were divided into three groups (two pigs each): Group A, 3-minute cooling mode; Group B, 6-minute intensive care mode; Group C, 12-minute intensive care mode. The back of the porcine skin was subjected to the relevant procedure, thrice daily for 15 days. Skin temperature was monitored to evaluate the thermal effects of the home-use device. In addition, changes in the collagen and elastin levels were examined through histological studies.Results: Visual inspection of the skin after device application did not show any skin damage at the treatment site. Examination of the skin surface and intradermal measurement of heat after treatment confirmed the deep heat generated by multi-energy sources. Histological staining revealed that accurate treatment of the target dermis layer effectively enhanced the deposition of both collagen and elastin.Conclusion: This study demonstrates the positive effect of using a home-use multi-energy-based device for skin rejuvenation. Utilizing the simultaneous and dynamic interplay of radiofrequency, light-emitting diode, and microcurrent along with sonophoresis and iontophoresis, proved to be a safe and efficient way to rejuvenate the skin.

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