Nickel-catalyzed stereo-controlled 2,3-hydrosilylation of 1,1-disubstituted allenes

초록

Directing regioselectivity and stereoselectivity in allene reactions has long been a significant challenge due to the multiple reactive pathways available. In this study, we report the development of a Ni-catalyzed regio- and stereoselective 2,3-hydrosilylation of 1,1-disubstituted allenes. Stereoselectivity was precisely controlled through the strategic modulation of ligand-induced steric effects and non-covalent interactions. Phenyl dibenzophosphole as the ligand enabled the selective formation of (Z)-allylsilanes, while tricyclohexylphosphine favored the production of (E)-allylsilanes. This work highlights the critical role of ligand-induced steric and non-covalent interactions in dictating regio- and stereoselectivity, offering new insights into Ni(ii) catalysis for stereoselective hydrosilylation. © 2025 The Royal Society of Chemistry.

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