Pentafluorobenzene: Promising Applications in Diagnostics and Therapeutics

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초록

Pentafluorobenzene (PFB) represents a class of aromatic fluorine compounds employed exclusively across a spectrum of chemical and biological applications. PFBs are credited with developing various chemical synthesis techniques, networks and biopolymers, bioactive materials, and targeted drug delivery systems. The first part of this review delves into recent developments in PFB-derived molecules for diagnostic purposes. In the latter segment, PFB's role in the domain of theragnostic applications is discussed. The review elucidates different mechanisms and interaction strategies applied in leveraging PFBs to formulate diagnostic and theragnostic tools, substantiated by proper examples. The utilization of PFBs emerges as an enabler, facilitating manifold reactions, improving materials' properties, and even opening avenues for explorative research.

키워드

pentafluorobenzenediagnosticstherapeuticsoptical imagingphotodynamictherapyNUCLEOPHILIC-SUBSTITUTIONVERSATILE PLATFORMFLUORESCENT-PROBESESTERNANOPARTICLESFLUORINEROUTEPOLYMERIZATIONDERIVATIVESACTIVATION
제목
Pentafluorobenzene: Promising Applications in Diagnostics and Therapeutics
저자
Nair, Ratish R.Seo, Eun WooHong, SeongjeJung, Kyung OhKim, Dokyoung
DOI
10.1021/acsabm.3c00676
발행일
2023-09
유형
Review
저널명
ACS Applied Bio Materials
6
10
페이지
4081 ~ 4099