Reduction in limb-movement complexity at term-equivalent age is associated with motor developmental delay in very-preterm or very-low-birth-weight infants
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초록

Reduced complexity during the writhing period can be crucial in the spontaneous movements of high-risk infants for neurologic impairment. This study aimed to verify the association between quantified complexity of upper and lower-limb movements at term-equivalent age and motor development in very-preterm or very-low-birth-weight infants. Video images of spontaneous movements at term-equivalent age were collected from very-preterm or very-low-birth-weight infants. A pretrained pose-estimation model and sample entropy (SE) quantified the complexity of the upper- and lower-limb movements. Motor development was evaluated at 9&#xa0;months of corrected age using Bayley Scales of Infant and Toddler Development, Third Edition. The SE measures were compared between infants with and without motor developmental delay (MDD). Among 90 infants, 11 exhibited MDD. SE measures at most of the upper and lower limbs were significantly reduced in infants with MDD compared to those without MDD (p&#x2009;<&#x2009;0.05). Composite scores in the motor domain showed significant positive correlations with SE measures at most upper and lower limbs (p&#x2009;<&#x2009;0.05). The results show that limb-movement complexity at term-equivalent age is reduced in infants with MDD at 9&#xa0;months of corrected age. SE of limb movements can be a potentially useful kinematic parameter to detect high-risk infants for MDD. © 2024. The Author(s).

키워드

ComplexityGeneral movementsMotor developmentPose estimationPretermSample entropyLOWER-EXTREMITY MOVEMENTSTIME-SERIES ANALYSISGENERAL MOVEMENTSEARLY MARKERENTROPYIDENTIFICATIONASSESSMENTS
제목
Reduction in limb-movement complexity at term-equivalent age is associated with motor developmental delay in very-preterm or very-low-birth-weight infants
저자
Park, Myung WooShin, Hyung-IkBang, Moon SukKim, Don-KyuShin, Seung HanKim, Ee-KyungLee, Eun SunShin, Hyun IeeLee, Woo Hyung
DOI
10.1038/s41598-024-59125-0
발행일
2024-04
유형
Article
저널명
Scientific Reports
14
1

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