Quantitative investigations on thermal response of adipose tissue to focused ultrasonic energy

초록

Thermal responses of adipose tissue to high intensity focused ultrasound (HIFU) were quantitatively evaluated for effective clinical lipolysis. A single-element HIFU transducer (4MHz and 4.5mm focal depth) was used in a linear motion to thermally treat the tissue at various acoustic energy densities and treatment gaps. Both interstitial temperature rise and denatured lesions increased with the energy density (up to 21.1 +/- 1.9K and 0.40 +/- 0.15 mm(2)). No thermal overlapping was observed due to selective application of the ultrasonic beams. The optimization of noninvasive HIFU treatment parameters may ensure clinical outcomes of HIFU-assisted lipolysis in terms of efficacy and safety. (C) 2017 The Japan Society of Applied Physics

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