The Fabrication of Cell Chips for Use as Bio-sensors

The Fabrication of Cell Chips for Use as Bio-sensors

초록

The development of biosensors for the detection of chemicals that are used by cells is of great interest to the pharmaceutical and environmental fields because of the potential for biosensors to measure unknown materials that cannot be detected based on their DNA or protein reactions. However, various problems associated with the introduction of cells to micro-devices, such as low reproducibility and sensitivity, must be overcome before biosensors can be used on a commercial scale. Here, we briefly discuss the cultivation of cells within microchips in vitro as well as the biosensor technologies that allow detection of cell properties and subsequent evaluation of specific analytes.

키워드

Cell-based biosensor; Extracellular matrix; Label-free detection; Peptides
제목
The Fabrication of Cell Chips for Use as Bio-sensors
제목 (타언어)
The Fabrication of Cell Chips for Use as Bio-sensors
저자
예철헌; 민준홍; 최정우
발행일
2007-12
저널명
BioChip Journal
권
1
호
4
페이지
219 ~ 227